Sophomore quarterback Mike Penix Jr. scored the game-winning points on a two-point conversion in overtime, rallying Indiana to a 36-35 upset of No. 8 Penn State at Bloomington, Ind. It was Indiana's first win over a Top 10 team in 33 years -- since beating No. 9 Ohio State 31-10 on Oct. 10, 1987.With Indiana down 28-20 at its own 25-yard line with less than two minutes to go in regulation, Penix drove the Hoosiers (1-0, 1-0 Big Ten) 75 yards and scored the game-tying touchdown and two-point conversion with 22 seconds left.
Indiana then flubbed a squib kick, however, giving Penn State a chance to win the game in regulation, but a 57-yard field goal attempt by kicker Jordan Stout fell short.
Sean Clifford started the overtime period with a 9-yard TD pass to wide receiver Parker Washington and Penn State added the extra point to go up 35-28.
That set the stage for Penix, who on third-and-goal from the 9, found wide receiver Whop Philyor for a touchdown to cut Penn State's lead to 35-34. Indiana coach Tom Allen then chose to go for two points, and Penix scrambled the 2 yards around left end and -- diving -- extending to hit the pylon with the ball while he was being driven down and out of bounds.
No. 1 Clemson 47, Syracuse 21
Trevor Lawrence threw for 289 yards and two touchdowns and running back Travis Etienne scored three touchdowns as the Tigers pulled away from the visiting Orange for their 27th consecutive victory against an Atlantic Coast Conference opponent.
Clemson (6-0, 5-0 ACC) never trailed and led 17-0 by the end of the first quarter. Syracuse (1-5, 1-4) pulled to within 27-21 when Rex Culpepper found Nykeim Johnson for an 83-yard touchdown bomb in the third quarter.
The Tigers scored the last 20 points to pull away. Andrew Booth Jr. returned a fumble by Culpepper for a score and Etienne (86 rushing) yards added fourth-quarter touchdowns of 9 and 1 yard to finish off the rout.
No. 2 Alabama 48, Tennessee 17
Despite losing star wide receiver Jaylen Waddle with a season-ending broken ankle on the opening kickoff, the visiting Crimson Tide got three rushing touchdowns from Najee Harris and 387 passing yards from Mac Jones in a Southeastern Conference blowout over the reeling Volunteers.
Waddle, who entered the game with 25 catches for 557 yards, suffered the ankle injury after starting the game with a kick return to the Crimson Tide 15-yard line. It didn't keep Alabama (5-0, 5-0 SEC) from beating its once-fierce rival for the 14th straight time. The Crimson Tide offense rolled up 587 yards and 30 first downs, scoring on four successive possessions in the first half and rolling off five touchdown drives of 70 yards or more.
Tennessee (2-3, 2-3) got 162 passing yards and two touchdown passes from Jarrett Guarantano but was overmatched throughout. Since reaching the No. 14 ranking, the Vols have lost three straight games.
No. 3 Notre Dame 45, Pittsburgh 3
Ian Book passed for 312 yards and three touchdowns, two of which went to Ben Skowronek, and the Fighting Irish rolled past host Pittsburgh in an ACC game. Book moved into second place in Notre Dame history in career touchdown passes with 63, trailing only Brady Quinn, who threw for 95 touchdowns (2003-06).
The Irish got three interceptions from its defense -- one each by Bo Bauer, Jeremiah Owusu-Koramoah and Nick McCloud -- and Isaiah Foskey blocked a punt and recovered it for a special teams touchdown. Notre Dame (5-0, 4-0 ACC) remained undefeated as it nears its potential showdown with No. 1 Clemson in two weeks.
Pitt (3-4, 2-4) dropped its fourth game in a row and gets a much-deserved week off, having already played seven games.
No. 5 Ohio State 52, Nebraska 17
Quarterback Justin Fields opened his Heisman Trophy campaign by completing 20 of 21 passes for 276 yards and two touchdowns as the Buckeyes pulled away from the Cornhuskers at Ohio Stadium.
Fields also ran for 54 yards on 15 carries and had a 17-yard TD run in the third quarter. That was quickly followed by a 55-yard fumble recovery and return for a score by cornerback Sevyn Banks as the Buckeyes blew open a game that was tied at 14 midway through the second quarter.
Ohio State (1-0, 1-0 Big Ten) outscored Nebraska (0-1, 0-1) in the second half, 28-3, dominating to the point that Buckeyes coach Ryan Day apologized for not taking a knee when his team reached the Nebraska 2-yard line in the final minute. Freshman quarterback Jack Miller ran for a touchdown, leading Day to say, "I feel bad about that."
No. 6 Oklahoma State, No. 17 Iowa State 21
Quarterback Spencer Sanders returned from injury to account for two touchdowns as the Cowboys held on for a win over the Cyclones in Big 12 play at Stillwater, Okla.
Sanders, who missed two games after suffering an ankle injury early in the opener against Tulsa, completed 20 of 29 passes for 235 yards, with one touchdown and two interceptions. He also ran for 71 yards and a score. Chuba Hubbard carried 25 times for 139 yards for the Cowboys (4-0, 3-0 Big 12).
Oklahoma State is the lone undefeated team in the Big 12, and in the process denied a chance for Iowa State (3-2, 3-1) to get to 4-0 in the conference for the first time in program history. Cyclones running back Breece Hall posted his fifth consecutive 100-yard game with a career-high 185 yards, including a 66-yard touchdown run that tied it 14-14 in the third quarter.
No. 9 Cincinnati 42, No. 16 SMU 13
Quarterback Desmond Ridder posted a 91-yard scoring run as one of his three rushing touchdowns and passed for a score as the Bearcats pulled away to beat the Mustangs in an American Athletic Conference clash of undefeated teams in Dallas.
Ridder rushed for a career-best 179 yards on just eight carries and completed 13 of 21 passes for 126 yards for the Bearcats (4-0, 2-0 AAC). Gerrid Doaks rushed for 105 yards and two scores, Josh Whyle caught a touchdown pass, and Jarell White recorded 13 tackles and a sack for Cincinnati.
Shane Buechele was 23-of-44 passing for 216 yards, one touchdown and one interception for SMU (5-1, 2-1). Rashee Rice caught a touchdown pass but the Mustangs totaled just 290 yards after entering the contest ranked fourth nationally at 563.2 per game.
No. 11 Miami 19, Virginia 14
The Hurricanes led 7-0 after 28 seconds and never trailed in a victory over the Cavaliers in ACC action in rainy Miami Gardens, Fla.
D'Eriq King lofted a 43-yard touchdown pass to a wide-open Mike Harley on the second play from scrimmage for the Hurricanes (5-1, 4-1 ACC), who handed the Cavaliers (1-4, 1-4) their fourth straight loss.
King completed 21 of 30 passes for 322 yards, with Harley hauling in 10 receptions for a career-high 170 yards. Miami outgained Virginia by a 444-366 margin, despite five sacks and 11 tackles for loss by the Cavaliers' defense.
No. 14 North Carolina 48, No. 23 NC State 21
In the first meeting with both teams ranked since 1993, Javonte Williams rushed for three second-half touchdowns as the host Tar Heels overwhelmed North Carolina State in Chapel Hill, N.C.
Williams scored on runs of 1, 5 and 27 yards, finishing with 160 yards on 19 carries. Michael Carter had a 16-yard touchdown run among his 106 rushing yards on 17 attempts for North Carolina (4-1, 4-1 ACC), while quarterback Sam Howell completed 18 of 29 passes for 252 yards and one touchdown.
With Devin Leary suffering a broken leg last week, NC State quarterback Bailey Hockman started and went 14-for-24 for 215 yards with a touchdown, and scored on a 1-yard run. Freshman Ben Finley entered in the second quarter for the visiting Wolfpack (4-2, 4-2). He went 13-for-20 for 143 yards and a touchdown, but the NC State defense was unable to slow the Tar Heels, who rolled out 578 yards of offense.
No. 18 Michigan 49, No. 21 Minnesota 24
Hassan Haskins led a punishing rushing attack with 82 yards and two touchdowns as the visiting Wolverines rolled past the Golden Gophers in Big Ten action.
Making his first career start, Wolverines quarterback Joe Milton completed 15 of 22 passes for 225 yards and a touchdown, and rushed for 52 yards and another score. Michigan gained 253 yards on 31 carries -- an 8.3 average -- and scored five rushing touchdowns.
The Wolverines (1-0, 1-0 Big Ten) led 21-10 after a wild first quarter and 35-17 at the half, getting big plays from their offense, defense, and special teams. For the Golden Gophers (0-1, 0-1), Mohamed Ibrahim rushed for 140 yards and two touchdowns.
Wake Forest 23, No. 19 Virginia Tech 16
Freshman walk-on Nick Andersen had three interceptions and a team-high 11 tackles to lift the Demon Deacons over the Hokies in an ACC game in Winston-Salem, N.C.
Quarterback Sam Hartman and Kenneth Walker III each rushed for a touchdown for Wake Forest (3-2, 2-2 ACC), which has won three in a row overall. The victory was Wake's first over Virginia Tech since a 6-3 double-overtime decision in 2014. Christian Beal-Smith rushed 13 times for 129 yards.
Hendon Hooker threw for 223 yards and rushed for 98 more for the Hokies (3-2, 3-2), who were whistled for 10 penalties for 112 yards en route to losing for the second time in three games.
No. 20 Kansas State 55, Kansas 14
Phillip Brooks had two punt-return touchdowns in the first half as the Wildcats dominated the Jayhawks in a Big 12 game at Manhattan, Kan.
It was the 12th consecutive victory for Kansas State (4-1, 4-0 Big 12) over Kansas, the longest winning streak in series history. It was also Kansas State's largest margin of victory over Kansas since a 59-7 victory in 2010. Kansas (0-5, 0-4) is now 7-94 in Big 12 play since 2009. The Jayhawks have not won multiple conference games since 2008.
Kansas State scored or set up 24 first-half points on special teams and added a defensive score in taking a 34-7 halftime lead. The Wildcats scored three touchdowns in the third quarter to erase any thoughts of a Kansas comeback.
No. 22 Marshall 20, Florida Atlantic 9
Grant Wells threw for 251 yards and a pair of touchdowns as the Thundering Herd got by the Owls in a matchup of Conference USA East Division contenders in Huntington, W. Va.
Wells completed 18 of 31 passes with two interceptions as the Thundering Herd (5-0, 3-0 C-USA) continued their best start since the 2014 team won its first 11 games. The loss snapped an eight-game winning streak for the Owls (1-1, 1-1).
Brenden Knox scored on a 58-yard reception in the first quarter and posted his fourth consecutive triple-digit rushing game, with 101 yards. Tavante Beckett (13) and Joshua Bowers (11) both were in double figures in tackles for the Herd, who got to FAU's Nick Tronti for five sacks and an interception. Tronti was 18 of 30 passing but for only 148 yards.
No. 25 Coastal Carolina 28, Georgia Southern 14
Playing their first game as a member of the Top 25, the Chanticleers looked the part when it mattered most, scoring two touchdowns in less than two minutes midway through the fourth quarter to beat the visiting Eagles at Conway, S.C.
CJ Marable snapped a tie with 8:53 remaining, when he took a pass from Fred Payton against busted coverage and dashed 24 yards for a 21-14 Coastal Carolina lead. Just moments later, Jaivon Heiligh returned a punt 40 yards to set up the Chanticleers (5-0, 3-0 Sun Belt) in prime position, leading to Reese White's 20-yard TD run. Georgia Southern (3-2, 1-2) got a 60-yard punt return for a touchdown by Wesley Kennedy III.
Payton passed for 252 yards and three touchdowns for Coastal Carolina in his first start after freshman starter Grayson McCall, who threw for 11 touchdowns with just one interception, was declared out with an upper-body injury.
--Field Level Media